The facility was renamed the Greenvale Sanatorium in ?1909. From 1924 to 1952, only female patients were admitted to Greenvale. From 1924, male patients were accommodated at Amhurst Sanatorium (south of Maryborough), which opened in December 1908. At the time of opening, it admitted only female patients.
In the 50 years following its opening, the need for such a service declined and the Sanatorium grew and progressed in other directions. New drug treatments for tuberculosis made the Sanatorium redundant, and this function of the facility was discontinued in 1956.
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